Acute aortic insufficiency associated with Wegener granulomatosis
| Autor: | Richard N. Hellman, Charles J. Mullany, Robert D. Leff |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Aortic valve
Male medicine.medical_specialty Systemic disease Adolescent Aortic Valve Insufficiency Antibodies Antineutrophil Cytoplasmic Diagnosis Differential medicine Sore throat Humans Anti-neutrophil cytoplasmic antibody Vascular disease business.industry Granulomatosis with Polyangiitis General Medicine medicine.disease Rash Surgery medicine.anatomical_structure Acute Disease cardiovascular system medicine.symptom Complication Vasculitis business |
| Zdroj: | Mayo Clinic proceedings. 74(9) |
| ISSN: | 0025-6196 |
| Popis: | Cardiac valvular involvement associated with Wegener granulomatosis is uncommon. We describe a 17-year-old male adolescent who sought medical attention because of a sore throat, arthralgias, low-grade fever, and fatigue of 3 weeks' duration. A rash was noted on his elbows, hands, and ankles; subsequently, a crusting lesion was noted in his internal nares, and infiltrates were detected on chest radiography. Blood cultures were negative for pathogens. An echocardiogram disclosed mild left ventricular enlargement with grade 2 aortic insufficiency, and Wegener granulomatosis was diagnosed based on an antineutrophil cytoplasmic antibody titer of 1:512. When blood cultures are negative for aortic valve endocarditis, a high index of clinical suspicion and antineutrophil cytoplasmic antibody testing may lead to the diagnosis of acute aortic insufficiency associated with Wegener granulomatosis. |
| Databáze: | OpenAIRE |
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