Adjuvant versus early salvage radiotherapy for prostate cancer patients: Time to move on
| Autor: | Alfonso Gomez-Iturriaga, Felipe Couñago, Carmen González San Segundo |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Oncology medicine.medical_specialty Neoplasias de la próstata Urology medicine.medical_treatment Prostatectomía 030232 urology & nephrology Patient subgroups Management of prostate cancer Androgen deprivation therapy Tratamiento médico 03 medical and health sciences Prostate cancer 0302 clinical medicine Radioterapia Early Medical Intervention Internal medicine medicine Humans Prostatectomy Salvage Therapy Adjuvant radiotherapy business.industry Prostatic Neoplasms Cáncer medicine.disease Survival Rate 030220 oncology & carcinogenesis Salvage radiotherapy Radiotherapy Adjuvant business Adjuvant |
| Zdroj: | Urologic Oncology: Seminars and Original Investigations. 39:351-356 |
| ISSN: | 1078-1439 |
| DOI: | 10.1016/j.urolonc.2021.02.012 |
| Popis: | In the management of prostate cancer , few treatments have caused as much controversy as adjuvant radiotherapy (ART) after radical prostatectomy in high-risk patients In the present article, we assess the exclusion and inclusion criteria of the 6 randomised trials and 5-year biochemical relapse-free survival and overall survival rates in order to identify the patient subgroups most likely to benefit from ART. We also evaluate treatment-related toxicity and the indications for androgen deprivation therapy . The main aim of this analysis was to determine whether the available evidence, which previously appeared to support ART, now favours early salvage radiotherapy. If so, perhaps we can finally resolve the controversy surrounding the optimal timing of postoperative radiotherapy. Sin financiación 2.954 JCR (2021) Q3, 47/90 Urology & Nephrology 0.818 SJR (2021) Q1, 19/108 Urology No data IDR 2021 UEM |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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