Autoimmune Pulmonary Alveolar Proteinosis during the Treatment of Idiopathic Inflammatory Myopathy

Autor:	Naoki, Shijubou, Takeyuki, Sawai, Taku, Hatakeyama, Satoru, Munakata, Masami, Yamazoe, Hirofumi, Chiba
Rok vydání:	2023
Předmět:	Internal Medicine General Medicine
Zdroj:	Internal Medicine. 62:445-448
ISSN:	1349-7235 0918-2918
Popis:	Approximately 50% of idiopathic inflammatory myopathies (IIMs) are associated with interstitial lung disease (ILD). Typically, IIM-ILD manifests as nonspecific interstitial pneumonia. We herein report a rare case of a 78-year-old man with autoimmune pulmonary alveolar proteinosis (PAP) that developed during IIM treatment. The diagnosis of autoimmune PAP was based on detecting anti-granulocyte-macrophage colony-stimulating factor antibodies. We postulated that PAP may have been induced by IIM treatment with prednisolone. Our case suggests that the possibility of autoimmune PAP should be considered in patients with lung lesions during the clinical course of IIM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8e334e8b4917657c67957d69a848a8 https://doi.org/10.2169/internalmedicine.9558-22 Zobrazit plný text záznamu