Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblast cells
Autor: | Hua Kong, Chaoying Wang, Jie Meng, Ning Gu, Sishen Xie, Xiaojin Qi, Haiyan Xu, Zhen Xu, Yu Zhang |
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Rok vydání: | 2010 |
Předmět: |
Bone Regeneration
Materials science Polyesters Cellular differentiation Composite number Nanoparticle Ferric Compounds Cell Line Magnetics Mice Tissue engineering medicine Animals General Materials Science Composite material Bone regeneration Cell Proliferation Osteoblasts Tissue Engineering Regeneration (biology) Cell Differentiation Osteoblast Electrospinning Extracellular Matrix Durapatite medicine.anatomical_structure Nanoparticles Biomedical engineering |
Zdroj: | Nanoscale. 2:2565 |
ISSN: | 2040-3372 2040-3364 |
DOI: | 10.1039/c0nr00178c |
Popis: | In this work, a paramagnetic nanofibrous composite film was fabricated with poly lactide, hydroxyapatite and γ-Fe(2)0(3) nanoparticles using the electrospinning technique. The composite film significantly enhanced the proliferation, differentiation and ECM secretion of the osteoblast cells under a static magnetic field, which offers promising application potentials in bone tissue engineering and bone regeneration therapy. |
Databáze: | OpenAIRE |
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