Effect of Diet and Physical Exercise Treatment on Insulin Resistance Syndrome of Schoolchildren
| Autor: | Tamas Szamosi, Agnes Sallai, Mensud Hatunic, Anna Szamosi, Zsuzsa Almássy, Zita Berla, Erika Tomsits, John J. Nolan, Antal Czinner |
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| Rok vydání: | 2008 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Adolescent Medicine (miscellaneous) Physical exercise Carbohydrate metabolism Body Mass Index Insulin resistance Risk Factors Diabetes mellitus Internal medicine medicine Humans Longitudinal Studies Obesity Exercise physiology Child Exercise Life Style Nutrition and Dietetics business.industry Lipid Metabolism medicine.disease Diet Treatment Outcome Endocrinology Blood pressure Diabetes Mellitus Type 2 Cardiovascular Diseases Area Under Curve Child Preschool Hypertension Female Insulin Resistance business Body mass index |
| Zdroj: | Journal of the American College of Nutrition. 27:177-183 |
| ISSN: | 1541-1087 0731-5724 |
| DOI: | 10.1080/07315724.2008.10719689 |
| Popis: | Insulin resistance syndrome (IRS) of schoolchildren may contribute to cardiovascular diseases (CVD) of young adults. The investigation of different steps, baseline screening parameters and treatment of IRS may help the prevention.Schoolchildren (53 boys and 61 girls age 5-17 years) because of adverse family history of CVD, hypertension, and obesity were investigated. Patients were divided into 3 groups according to baseline plasma glucose level (PGL) 120 and 180 min. after glucose consumption (GC): (1) PGLor = 5.5 mmol/L 180 min. after GC, (2) PGLor = 5.5 mmol/L 180 min. butor = 7.8 mmol/L 120 min. after GC (3) PGLor = 7.8 mmol/L 120 min. after GC. Body mass index (BMI), blood pressure (BP) and parameters of glucose and lipid metabolism were measured at baseline and after two year's lifestyle modification.No significant difference was found in the prevalence of cardiovascular risk factors (CRF) between groups 2 and 3. Fasting PGL5.5 mmol/L was found in 1, 2, and 6 cases; HOMA index4.4 in 7 (24%), 21 (37%), and 9 (35%) subjects; OGIS index400 in 3(10%), 29(51%) and 11 (42%) schoolchildren of groups 1, 2, 3, respectively. Lifestyle modification significantly improved BMI, systolic BP, serum triglyceride and HDL-cholesterol levels and insulin sensitivity.PGL measured 180 minutes after GC may define an important subgroup of pre-diabetic children. The similar prevalance of CRF in both praediabetic groups underlines the importance of this subgroup. Lifestyle modification for two years improves CRF in this population. |
| Databáze: | OpenAIRE |
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