Rectal neoplasia extending to the dentate line: clinical outcomes of endoscopic submucosal dissection
| Autor: | Giulio Antonelli, Gianluca Andrisani, J Hamanaka, Kingo Hirasawa, Francesco Maria Di Matteo, Cesare Hassan, Takehide Fukuchi, Guido Costamagna |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Endoscopic Mucosal Resection Endoscopy Gastrointestinal 03 medical and health sciences 0302 clinical medicine Humans Medicine Aged Retrospective Studies Gastrointestinal endoscopy Aged 80 and over medicine.diagnostic_test Rectal Neoplasms business.industry Gastroenterology Endoscopic submucosal dissection Middle Aged Endoscopy Treatment Outcome 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Radiology Line (text file) Colorectal Neoplasms business |
| Zdroj: | Scandinavian Journal of Gastroenterology. 55:1363-1368 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.1080/00365521.2020.1825791 |
| Popis: | The European Society of Gastrointestinal Endoscopy (ESGE) and the Japan Gastroenterological Endoscopy Society (JGES) give no specific recommendations on the best treatment for colorectal neoplasia involving the dental line (DLCN).Aim of this study was to analyse efficacy and safety of Endoscopic Submucosal Dissection in the treatment of colorectal neoplasia involving the dentate line (DLCN) compared to non-DLCN.Retrospective study.We retrospectively evaluated all consecutive patients undergoing ESD for rectal neoplasia at two endoscopical tertiary referral centers (Italy and Japan) from January 2008 to December 2019.Anthropometric, clinical, procedural, and follow-up data was collected, analysed, and compared between patients with DLCN and patients with non-DLCN.Overall, 314 patients were enrolled (163 female, 51.9%). Mean age was 68 years (range, 32-92 years). En-bloc resection was achieved in 311/314 (99%) patients. Lesion size was higher in DLCN group than in the non-DLCN group (46.1 vs 38.9 mm;Retrospective study design.ESD seems to be safe and effective in the treatment of colorectal neoplasia involving the dentate line and can be considered the best therapeutic strategy. |
| Databáze: | OpenAIRE |
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