A retinopathy on Guam with high prevalence in Lytico-Bodig
| Autor: | James V. McDarby, Donald B. Calne, Lawrence Lavine, Terry A. Cox, John C. Steele |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
Male medicine.medical_specialty Frequency of occurrence Fundus Oculi Eye disease Retinal Diseases medicine Electroretinography Prevalence Humans Amyotrophic lateral sclerosis Pigment Epithelium of Eye Aged Aged 80 and over High prevalence business.industry Incidence (epidemiology) Incidence Amyotrophic Lateral Sclerosis Pigmentary Retinopathy Parkinson Disease Middle Aged medicine.disease Dermatology Surgery Ophthalmoscopy Ophthalmology Electrooculography Guam Female business Retinopathy |
| Zdroj: | Ophthalmology. 96(12) |
| ISSN: | 0161-6420 |
| Popis: | A pigmentary retinopathy resembling that sometimes seen in posterior ophthalmomyiasis interna was found in 26 (53.1 %) of 49 Chamorro patients from Guam who have Lytico-Bodig (also known as amyotrophic lateral sclerosisParkinson ism-dementia complex of Guam). In nine cases, the retinopathy was bilateral. Similar changes were found in 6 (16.2%) of 37 clinically normal individuals from southern villages on Guam that have a high incidence of LyticoBodig, and in 1 (3.1%) of 32 individuals from Saipan, an island north of Guam that has a low incidence of the disease. These results indicate the possibility of an association between Lytico-Bodig and a retinopathy on Guam that may be parasitic in origin. Occurrence of a similar association in other debilitating diseases on Guam and frequency of occurrence of retinopathy in Guamanians with Lytico-Bodig after leaving Guam have yet to be determined. |
| Databáze: | OpenAIRE |
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