The nature of impairments of memory in patients with end-stage renal disease (ESRD)
Autor: | John Harris, Daniel J. W. Jones, Rebecca Hadid, Emma Vaux, Laurie T. Butler, Rebecca Kean |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty media_common.quotation_subject Experimental and Cognitive Psychology Disease Neuropsychological Tests Audiology Stimulus (physiology) End stage renal disease Developmental psychology Behavioral Neuroscience Memory task Surveys and Questionnaires Perception Activities of Daily Living medicine Humans In patient Renal Insufficiency Chronic Healthy aging Aged media_common Memory Disorders Depression Middle Aged Mental Recall Female Implicit memory Mental Status Schedule Psychology Dialysis |
Zdroj: | Physiology & Behavior. 147:324-333 |
ISSN: | 0031-9384 |
DOI: | 10.1016/j.physbeh.2015.05.008 |
Popis: | Possible impairments of memory in end-stage renal disease (ESRD) were investigated in two experiments. In Experiment 1, in which stimulus words were presented visually, participants were tested on conceptual or perceptual memory tasks, with retrieval being either explicit or implicit. Compared with healthy controls, ESRD patients were impaired when memory required conceptual but not when it required perceptual processing, regardless of whether retrieval was explicit or implicit. An impairment of conceptual implicit memory (priming) in the ESRD group represented a previously unreported deficit compared to healthy aging. There were no significant differences between pre- and immediate post-dialysis memory performance in ESRD patients on any of the tasks. In Experiment 2, in which presentation was auditory, patients again performed worse than controls on an explicit conceptual memory task. We conclude that the type of processing required by the task (conceptual vs. perceptual) is more important than the type of retrieval (explicit vs. implicit) in memory failures in ESRD patients, perhaps because temporal brain regions are more susceptible to the effects of the illness than are posterior regions. |
Databáze: | OpenAIRE |
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