Seasonal fluctuations of glial fibrillary acidic protein (GFAP) immunoreactivity in the rat suprachiasmatic nucleus
| Autor: | Ferenc Szalay, Balázs Gerics, Ferenc Hajós |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
endocrine system medicine.medical_specialty animal structures Biological clock General Biochemistry Genetics and Molecular Biology Biological Clocks Internal medicine Glial Fibrillary Acidic Protein medicine Animals Rats Wistar Intact male General Environmental Science Glial fibrillary acidic protein biology Suprachiasmatic nucleus Immunohistochemistry Neuronal pathway Rats Endocrinology nervous system Neurology Hypothalamus biology.protein Suprachiasmatic Nucleus Seasons sense organs Orchiectomy hormones hormone substitutes and hormone antagonists |
| Zdroj: | Acta Biologica Hungarica. 56:199-204 |
| ISSN: | 1588-256X 0236-5383 |
| DOI: | 10.1556/abiol.56.2005.3-4.3 |
| Popis: | The pacemaker of the "biological clock", the suprachiasmatic nucleus (SCN) of the hypothalamus was studied in intact male rats for glial fibrillary acidic protein (GFAP) a specific marker for astrocytes. Immunohistochemical reactions were carried out in winter (January-February) and in summer (June-July). In winter the GFAP-immunoreactivity of the SCN was found low whereas in summer it was high. Gonadectomy reduced differences. Since photic stimuli that apparently trigger the observed differences reach the SCN through identified neuronal pathways we conluded that the reaction of astrocytes is an indicator of seasonally altered neuronal function in the SCN. |
| Databáze: | OpenAIRE |
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