EVALUATION OF EXTRACORPOREAL GAS EXCHANGE DEVICE HEMOLUNG FOR POTENTIAL APPLICATION IN PEDIATRIC PRACTICE
| Autor: | E. A. Mussin, D. S. Bulanin, R. G. Jeffries, Zh. Sh. Zhumadilov, F. S. Olzhayev, W. J. Federspiel |
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| Rok vydání: | 2015 |
| Předmět: |
extracorporeal gas exchange
Transplantation medicine.medical_specialty Materials science pediatrics RD1-811 Pressure data Oxygenation Surgery chemistry.chemical_compound chemistry Bovine blood Carbon dioxide medicine Immunology and Allergy severe respiratory failure Extracorporeal gas exchange oxygenation Oxygenator Biomedical engineering Blood gas analysis |
| Zdroj: | Vestnik Transplantologii i Iskusstvennyh Organov, Vol 16, Iss 4, Pp 125-134 (2014) |
| ISSN: | 1995-1191 |
| DOI: | 10.15825/1995-1191-2014-4-125-134 |
| Popis: | Aim . The main purpose of this work is to evaluate the Hemolung pumping ability and gas exchange effectiveness while using the catheters of smaller diameter and blood fl ow rates, applied in pediatrics. Material and methods . The bench testing of the device with pediatric catheters has been performed. The bovine blood and carboxymethylcellulose water solution were used as a model. The device operation data, blood gas analysis and hydrodynamic pressure data were collected. Results. The pump curve results show that at the maximum rotation rate the Hemolung device was able to achieve blood fl ow rates substantially greater than targeted 280 ml/min that is used in pediatrics. The calculated operating curve plotted against the observed pressure-fl ow relationships shows that the device could be able to operate against pressure heads of 80 and 100 mm Hg. In general, carbon dioxide elimination rate increased along with increase of the rotation rate, reaching maximum levels of 168 ± 0.3 ml CO2/min at 1750 RPM and a blood fl ow rate of 670 ± 42 ml/min. As a passive oxygenator, the small gas exchange fi ber surface area of the Hemolung resulted in oxygen saturations of 81% and 78% at 1.5 and 2.0 L/min, respectively. Conclusion. The results of this study show the prospect of application of the Hemolung system in pediatrics. |
| Databáze: | OpenAIRE |
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