Re-infection following sustained virological response with a different hepatitis C virus genotype: implications for infection control policy
| Autor: | Veronica M. Francis, Frank E. Murray, Margaret Duffy, John O'Regan, Sharon Dwyer, Peter J. Conlon, Jeff Connell, Michelle M. O’Shaughnessy, Lelia Thornton |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Hepatitis C virus medicine.disease_cause Clinical Reports Pegylated interferon Genotype Epidemiology medicine Infection control Dialysis re-infection Transplantation business.industry virus diseases Hepatitis C medicine.disease infection control digestive system diseases Nephrology Immunology Clinical Cases dialysis Hemodialysis hepatitis C sustained virological response business medicine.drug |
| Zdroj: | Clinical Kidney Journal |
| ISSN: | 2048-8513 2048-8505 |
| DOI: | 10.1093/ckj/sfs040 |
| Popis: | We report the case of a 45-year-old haemodialysis patient who achieved a sustained virological response (SVR) following pegylated interferon therapy for hepatitis C virus (HCV) genotype 2 infection. He was subsequently cohorted with other HCV-infected dialysis patients and became re-infected with HCV genotype 3a. Epidemiological and molecular investigations identified a highly viraemic HCV genotype 3a-infected dialysis patient as the likely source of this infection. This critical incident informed a revision to local and national infection control policy regarding the dialysis management of patients who achieve an SVR following anti-viral treatment. |
| Databáze: | OpenAIRE |
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