Serum levels of VEGF and basic FGF in the subacute phase of myocardial infarction
| Autor: | Yoshiyuki Katsuyama, Yasuhiro Akai, Yasunobu Sasaki, Kazuhiro Dohi, Sota Tsujimura, Atsuhiko Kawamoto, Hiroyuki Kawata, Shinichi Fujimoto, Yasuhiro Sakaguchi, Toshio Hashimoto, Eiji Takase, Masayuki Iwano |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
Vascular Endothelial Growth Factor A medicine.medical_specialty medicine.drug_class Angiogenesis Basic fibroblast growth factor Myocardial Infarction Enzyme-Linked Immunosorbent Assay Endothelial Growth Factors chemistry.chemical_compound Internal medicine medicine Humans cardiovascular diseases Myocardial infarction Lymphokines biology business.industry Heparin Vascular Endothelial Growth Factors Anticoagulant Anticoagulants Middle Aged medicine.disease Pathophysiology Vascular endothelial growth factor Endocrinology chemistry Case-Control Studies biology.protein Creatine kinase Female Fibroblast Growth Factor 2 Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | International journal of cardiology. 67(1) |
| ISSN: | 0167-5273 |
| Popis: | We examined serial changes in serum levels of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) measured by ELISAs in 45 patients with acute myocardial infarction (AMI) who received heparin intravenously for 3 to 5 days after the onset and in 30 control subjects with an old myocardial infarction. To evaluate the effect of heparin on these serum levels, heparin was administered intravenously in 10 patients with AMI on day 21. Blood samples were obtained from all AMI patients on days 1, 2, 3, 7, 14, 21, and 28 and from 10 AMI patients before and 1 h after heparin administration. Serum VEGF level was significantly reduced after heparin administration (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect