Carotid plague formation is associated with ankle-brachial index in elderly people
| Autor: | Ting-Jun Hu, Yuan Zhong, Chan-Chan Xu, Feng-Feng Pan, Guo-Xiang Fu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Aging
medicine.medical_specialty Pulse Wave Analysis Logistic regression Carotid Intima-Media Thickness 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Elderly people Humans Ankle Brachial Index cardiovascular diseases 030212 general & internal medicine Pulse wave velocity Aged Plague business.industry Ultrasound body regions Carotid artery plaque medicine.anatomical_structure Cross-Sectional Studies Quartile cardiovascular system Cardiology Geriatrics and Gerontology Ultrasonography Ankle business human activities 030217 neurology & neurosurgery |
| Zdroj: | Aging clinical and experimental research. 32(11) |
| ISSN: | 1720-8319 |
| Popis: | This study aimed at examining whether ankle–brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) were independently associated with carotid Intima-media thickness (CIMT) or carotid artery plaque (CAP) in elderly people. A cross-sectional analysis was performed in 155 individuals aged over 75 years who underwent the measurements of ABI and baPWV. Low ABI was defined as ABI ≤ 1.0. High baPWV was defined as baPWV > 2000 cm/s. The CIMT and CAP were measured with a B-mode tomographic ultrasound system. Neither ABI nor baPWV was associated with CIMT in this elderly population. The group with low ABI (≤ 1.0) was significantly associated with a higher prevalence of carotid plaque (P = 0.001), while the relationship between baPWV and prevalence of carotid plaque was not found. Linear regression analysis showed that the value of ABI was significantly associated with the thickness of carotid plaque. Even in the full adjusted model, each 0.01unit ABI decreasing still increased 0.1663 mm of carotid plaque thickness (P = 0.004). Logistic Regression Analysis demonstrated that ABI lower than 1.0 had predictive value in the formation of carotid plaque with top quartile thickness (OR 2.834, 95% CI 1.131–7.099, P = 0.026). Furthermore, individuals with low ABI (≤ 1.0) were more likely to form hypoechoic carotid plaques according to ultrasonography. Low ABI but not high baPWV was associated with the formation of carotid plaque. Furthermore, ABI was significantly associated with the thickness and morphology of carotid plaque in elderly people. |
| Databáze: | OpenAIRE |
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