Inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients

Autor:	M.-A. Dagnelie, Brigitte Dréno, Amir Khammari, Emmanuel Montassier, Stéphane Corvec, Carine Mounier
Rok vydání:	2019
Předmět:	0301 basic medicine Adult medicine.medical_specialty Adolescent Population Dermatology Biochemistry 030207 dermatology & venereal diseases 03 medical and health sciences Young Adult 0302 clinical medicine Acne Vulgaris Medicine Humans Microbiome education Molecular Biology Staphylococcaceae Acne Skin education.field_of_study Propionibacteriaceae Back integumentary system biology business.industry Inflammatory skin disease Microbiota biology.organism_classification medicine.disease Pathophysiology 030104 developmental biology Case-Control Studies Face business Microbiota composition
Zdroj:	Experimental dermatology. 28(8)
ISSN:	1600-0625
Popis:	Acne is the most common inflammatory skin disease, affecting up to 85% of the 11-30 years old world population. Skin microbiota appears as a key player involved in several skin dermatoses physiopathology. Here, we show that inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients but also on the face of patients where acne was scored as mild to moderate, comparing with healthy controls. Changes were observed particularly on skin commensals Propionibacteriaceae, Staphylococcaceae and Enterococcaceae families, suggesting the importance of the balance between skin commensals to maintain skin homeostasis and control skin inflammatory process.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4cda31be177a2908c1714d82df7024 https://pubmed.ncbi.nlm.nih.gov/31173650 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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