Characteristics of Diffusion in the Corticospinal Tract of Patients with Early Stage of Schizophrenia: Diffusion Tensor Magnetic Resonance Imaging
| Autor: | S. V. Sidorin, T. A. Akhadov, O. V. Lukovkina, Irina Lebedeva, M. V. Ublinskii, N. A. Semenova, Kaleda Vg, Barkhatova An |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Materials science Internal capsule Adolescent Cerebral Peduncle Pyramidal Tracts Nerve fiber General Biochemistry Genetics and Molecular Biology Diffusion Young Adult Nuclear magnetic resonance Nerve Fibers Body Water Internal Capsule Fractional anisotropy medicine Humans Diffusion (business) Medulla Oblongata Quantitative Biology::Neurons and Cognition Motor Cortex General Medicine White Matter medicine.anatomical_structure Diffusion Tensor Imaging Corticospinal tract Schizophrenia Anisotropy Diffusion MRI Tractography Motor cortex |
| Zdroj: | Bulletin of experimental biology and medicine. 159(1) |
| ISSN: | 1573-8221 |
| Popis: | Specific features of diffusion in the cerebral corticospinal tract of patients with early stages of schizophrenia were studied using methods of diffusion tensor magnetic-resonance imaging and magnetic resonance spectroscopy. A decrease in the coefficient of fractional anisotropy in the posterior limb of the internal capsule and an increase in diffusion coefficient in the radiate crown and motor cortex were observed. The results reflect different mechanisms of changes in water diffusion in various areas of the corticospinal tract: changes in nerve fiber microstructure in the internal capsule of the left hemisphere and a decrease in their density in the motor cortex and radiate crown. |
| Databáze: | OpenAIRE |
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