Chronic granulomatous disease

Autor: Prasanna K. Moorthy, Pradeep S Nair, K. Preethi, Sabeena Jayapalan, S Suprakasan
Rok vydání: 2005
Předmět:
Zdroj: Indian Journal of Dermatology, Venereology and Leprology, Vol 71, Iss 3, Pp 199-201 (2005)
ISSN: 0378-6323
DOI: 10.4103/0378-6323.16240
Popis: A 2½-year-old child presented with multiple discrete granulomatous lesions on the face and flexural regions since the age of 2 months along with lymphadenopathy. The patient also had recurrent bouts of pyodermas and respiratory tract infections. Biopsy of the lesion showed necrosis of tissue with suppuration and histiocytes but no evidence of tuberculosis, fungal infections or atypical mycobacteria. Lymph node biopsy also showed necrosis with suppuration but no infective organism. Nitroblue tetrazolium test was negative indicating that the neutrophils failed to oxidize the dye. We are reporting here a rare case of chronic granulomatous disease.
Databáze: OpenAIRE