Mechanochemical Endovenous Ablation of Varicose Veins in Pediatric Patients with Klippel-Trénaunay Syndrome: Feasibility, Safety, and Initial Results
| Autor: | Mauricio Silva, Mariela Cabezas, Darío Teplisky, Alejandro Oliva, Ioná Szhafir, Sergio Sierre, Gonzalo Lambert, M. Garriga |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Ablation Techniques
Male Klippel-Trenaunay-Weber Syndrome medicine.medical_specialty Time Factors Klippel-Trenaunay syndrome Adolescent medicine.medical_treatment Venography 030218 nuclear medicine & medical imaging Sodium Tetradecyl Sulfate Varicose Veins 03 medical and health sciences 0302 clinical medicine Recurrence Sclerotherapy Varicose veins Occlusion medicine Humans Radiology Nuclear Medicine and imaging Child Retrospective Studies medicine.diagnostic_test business.industry Endovascular Procedures Retrospective cohort study Ablation medicine.disease Sclerosing Solutions Sodium tetradecyl sulfate Surgery Catheter Treatment Outcome Child Preschool 030220 oncology & carcinogenesis Feasibility Studies Female medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Journal of Vascular and Interventional Radiology. 32:80-86 |
| ISSN: | 1051-0443 |
| DOI: | 10.1016/j.jvir.2020.08.019 |
| Popis: | Purpose To evaluate feasibility, safety, and results of endovenous mechanochemical ablation (MOCA) for treatment of persistent embryonic and dysplastic veins in pediatric patients with Klippel-Trenaunay syndrome (KTS). Materials and Methods Thirteen MOCA procedures were performed in 11 patients (age range, 4–16 years) with KTS and symptomatic persistent embryonic or dysplastic veins during a 24-month period. All patients were evaluated with color Doppler (CD) ultrasound (US), contrast-enhanced MR imaging, and venography to assess the anatomy of the target vessels and patency of the deep venous system. All procedures were performed under general anesthesia with a ClariVein catheter and liquid sodium tetradecyl sulfate as the sclerosing agent. US and fluoroscopic guidance were used in all cases. Technical success rate, primary occlusion rate, adverse effects, and recanalization rates were evaluated. Clinical and radiological (CD US) controls were performed 1 day, 7 days, 1 month, and 6 months after the procedure and once a year thereafter, with a mean follow-up of 16 months (range, 6–25 months). Results Technical success and primary occlusion were achieved in all patients with no adverse events. During the follow-up period, CD US demonstrated partial recanalization and symptom recurrence in 2 patients (18%), 14 and 18 months after the initial procedure. These 2 patients had a second ablation procedure with no recanalization or symptom recurrence during the subsequent follow-up period. Conclusions MOCA is feasible and appears to be a safe and effective technique for treatment of varicose veins in pediatric patients with KTS. |
| Databáze: | OpenAIRE |
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