Synthesis of 1-indanones with a broad range of biological activity
| Autor: | Dorota Szczęsna, Marek Koprowski, Marika Turek, Piotr Bałczewski |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Chemistry Range (biology) Organic Chemistry Patent literature Biological activity biological activity Nazarov reaction Review 010402 general chemistry 01 natural sciences 0104 chemical sciences lcsh:QD241-441 lcsh:Organic chemistry Diels–Alder reaction Organic chemistry lcsh:Q 1-indanones lcsh:Science Friedel–Crafts reaction |
| Zdroj: | Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 451-494 (2017) Beilstein Journal of Organic Chemistry |
| ISSN: | 1860-5397 |
| Popis: | This comprehensive review describes methods for the preparation of 1-indanones published in original and patent literature from 1926 to 2017. More than 100 synthetic methods utilizing carboxylic acids, esters, diesters, acid chlorides, ketones, alkynes, alcohols etc. as starting materials, have been performed. This review also covers the most important studies on the biological activity of 1-indanones and their derivatives which are potent antiviral, anti-inflammatory, analgesic, antimalarial, antibacterial and anticancer compounds. Moreover, they can be used in the treatment of neurodegenerative diseases and as effective insecticides, fungicides and herbicides. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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