Antioxidant and antibacterial activities and polyphenolic constituents of Helianthemum sessiliflorum Pers

Autor: Mohammed Benkhaled, Imane Benabdelaziz, Hamada Haba, Laurence Marcourt, Jean-Luc Wolfender
Rok vydání: 2016
Předmět:
DPPH
Flavonoid
Ethyl acetate
Plant Science
Acetates
030226 pharmacology & pharmacy
01 natural sciences
Biochemistry
Antioxidants
Analytical Chemistry
Picrates/chemistry
chemistry.chemical_compound
0302 clinical medicine
Cistaceae/chemistry
Free Radical Scavengers/chemistry/pharmacology
Organic chemistry
chemistry.chemical_classification
ddc:615
Traditional medicine
Free Radical Scavengers
Anti-Bacterial Agents
Biphenyl compound
Phytochemical
Phenols/isolation & purification/pharmacology
Biphenyl Compounds/chemistry
Antibacterial activity
Plant Components
Aerial/chemistry
Microbial Sensitivity Tests
Anti-Bacterial Agents/pharmacology
03 medical and health sciences
1-Butanol
Phenols
Picrates
Plant Extracts/chemistry/pharmacology
Flavonoids
Flavonoids/isolation & purification/pharmacology
Bacteria
Plant Extracts
010405 organic chemistry
Biphenyl Compounds
Organic Chemistry
Polyphenols
Cistaceae
Plant Components
Aerial
0104 chemical sciences
Antioxidants/pharmacology
Bacteria/drug effects
chemistry
Polyphenol
Solvents
Polyphenols/chemistry/pharmacology
Zdroj: Natural Product Research, Vol. 31, No 6 (2017) pp. 686-690
ISSN: 1478-6427
1478-6419
DOI: 10.1080/14786419.2016.1209669
Popis: In this study, the various extracts of aerial parts of Helianthemum sessiliflorum Pers. were examined in vitro for possible source of antioxidants and for antibacterial activity. The antioxidant activity was performed by DPPH radical scavenging method which showed that ethyl acetate extract possessed the best antioxidant potential (IC50 = 32.75 ± 2.07 μg/mL). The significant linear correlation was realised between the values of the total phenolic/flavonoid content and antioxidant activity of plant extracts. The ethyl acetate and n-butanol extracts showed moderate antibacterial activity. In addition, the phytochemical study of n-butanol extract afforded nine known phenolic compounds (1–9). This is the first report of six of them (1, 3, 5–8) in Cistaceae family. The structural identification of the isolated compounds was achieved using several spectroscopic methods.
Databáze: OpenAIRE
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