Collagen metabolism in small intestinal anastomosis
| Autor: | H. Jiborn, Bengt Zederfeldt, Kent Jönsson |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Male
medicine.medical_specialty Pathology Time Factors Ileum Anastomosis Surgical anastomosis Intestinal mucosa Internal medicine Tensile Strength Ultimate tensile strength medicine Animals Intestinal Mucosa Wound Healing Sutures business.industry Rats Inbred Strains General Medicine Metabolism Small intestine Rats medicine.anatomical_structure Endocrinology Surgery Collagen Wound healing business |
| Zdroj: | American journal of surgery. 154(3) |
| ISSN: | 0002-9610 |
| Popis: | Collagen metabolism in the small intestinal wall during the first week of anastomotic healing in operated and nonoperated rats was studied. During this period, marked changes in anastomotic strength have been observed. A general and marked increase of collagen synthesis was found throughout the intestine already on the second day. This resulted in increased collagen content. Collagen concentration remained relatively unchanged despite an increase in collagen content as a result of concomitant increase of noncollagenous substances. The previously reported loss of anastomotic strength in the early phase of healing could not be explained by changes in collagen content or metabolism in this study. Cutting of sutures seems to be due to a local process. After 4 days, collagen content increased predominantly in the anastomotic region. It correlated well to the previously observed increase of anastomotic strength. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|