Reduced exercise capacity and clinical outcomes following acute myocardial infarction
| Autor: | Takashi Okajima, Hiroki Kojima, Akihito Tanaka, Ruka Yoshida, Takayuki Mitsuda, Kenshi Hirayama, Yusuke Hitora, Kenji Furusawa, Hiroshi Tashiro, Naoki Iwakawa, Takeshi Adachi, Kenji Arai, Hideki Ishii, Toyoaki Murohara, Yasuhiro Ogawa, Nariko Motomura, Motoharu Hayashi, Hajime Imai, Katsuhiro Kawaguchi |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Population Myocardial Infarction Diastole 030204 cardiovascular system & hematology Risk Assessment 03 medical and health sciences Oxygen Consumption Percutaneous Coronary Intervention 0302 clinical medicine Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Myocardial infarction education Aged education.field_of_study Exercise Tolerance business.industry Percutaneous coronary intervention Recovery of Function Middle Aged Vascular surgery medicine.disease Cardiac surgery Functional Status Treatment Outcome Heart Disease Risk Factors Heart failure Conventional PCI Exercise Test Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Heart and Vessels. 35:1044-1050 |
| ISSN: | 1615-2573 0910-8327 |
| Popis: | Reduced exercise capacity is known to be an important predictor of poor prognosis and disability in patients with cardiovascular diseases and chronic heart failure, and even members of the general population. However, data about exercise capacity assessed by cardiopulmonary exercise testing (CPX) in acute myocardial infarction (AMI) patients who underwent primary percutaneous coronary intervention (PCI) is scarce. Among 594 consecutive AMI patients who underwent primary PCI, we examined 136 patients (85.3% men, 64.9 ± 11.9 years) who underwent CPX during hospitalization for AMI. CPX was usually performed 5 days after the onset of AMI. Reduced exercise capacity was defined as peak VO2 ≤ 12. Clinical outcomes including all-cause death, myocardial infarction, and hospitalization due to heart failure were followed. Among 136 patients, reduced exercise capacity (peak VO2 ≤ 12) was seen in 38 patients (28%). Patients with reduced exercise capacity were older, more likely to have hypertension, and had lower renal function. In echocardiography, patients with reduced exercise capacity had higher E/e’ and larger left atrial dimension. Multivariate logistic analysis showed that E/e’ (OR 1.19, 95% CI 1.09–1.31, p 12 (p |
| Databáze: | OpenAIRE |
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