The Therapy with Oral Anticoagulants in Patients with Atrial Fibrillation in Outpatient and Hospital Settings (Data from RECVASA Registries)
| Autor: | V. V. Yakusevich, Oxana Drapkina, E. Y. Andreenko, M. A. Panagopulu, A. V. Zagrebelnyy, K. G. Pereverzeva, Sergey Boytsov, E. V. Kudryashov, E. E. Fedotova, V. P. Mikhin, E. Yu. Okshina, A. N. Vorobyev, S. Yu. Martsevich, T. A. Gomova, S. S. Yakushin, V. G. Klyashtorny, M. N. Valiakhmetov, E. M. Pozdnyakova, M. M. Loukianov, Yu. V. Maslennikova |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
RM1-950 non-vitamin k antagonist oral anticoagulant Internal medicine follow-up Medicine Outpatient clinic Diseases of the circulatory (Cardiovascular) system Pharmacology (medical) In patient atrial fibrillation Stroke therapy with oral anticoagulants business.industry Incidence (epidemiology) Warfarin registries Atrial fibrillation medicine.disease outpatient and hospital settings Thromboembolic risk warfarin Hospital treatment RC666-701 Therapeutics. Pharmacology Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Racionalʹnaâ Farmakoterapiâ v Kardiologii, Vol 15, Iss 4, Pp 538-545 (2019) |
| ISSN: | 2225-3653 1819-6446 |
| Popis: | Aim. To evaluate an incidence of oral anticoagulants (OAC) administration during longterm follow-up period in patients with atrial fibrillation (AF) enrolled in outpatient and hospital RECVASA registries.Material and methods. 3169 patients with AF were enrolled in outpatient registries RECVASA (Ryazan), RECVASA AF-Yaroslavl and hospital registries RECVASA AF (Moscow, Kursk, Tula), age 70.9±10.7 years, 43.1% men. The incidence of OAC administration was evaluated in hospital and outpatient settings, including longterm follow-up period (2-6 years).Results. OAC were administrated only in 42.2% of cases (1335 from 3169 patients; age 69.1±10.4 years, 43% men), including warfarin (817 patients; 26%) and non-vitamin K antagonist oral anticoagulants (NOAC) – 518 (16%). Patients with permanent and persistant types of AF had lower incidence of OAC administration (43% and 40%) than in cases of paroxysmal type (47.6%, p0.05) contrary to the pronounced difference of thromboembolic risk in these groups (6.14±1.34 and 3.77±1.39; рConclusions. RECVASA registries in 5 regions of Russia revealed low incidence of OAC administration. The risk of thromboembolic events was higher in patients with AF and no OAC administration compared with patients who received OAC. Patients with paroxysmal type of AF received OAC more often than those with permanent type. There were no significant differences of incidence of OAC therapy in patients with and without history of stroke. Both questioning of patients with AF and analysis of medical cards in outpatient clinics revealed higher incidence of OAC administration after 4-6 years of follow-up compared with the stage of enrollment in registries. |
| Databáze: | OpenAIRE |
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