| Autor: |
Yongshi Shen, Liuxin Yang, Jinsen Weng, Yiping Zhang, Zhizhong Lin, Qingzhong Lin, Min Xiao, Jingping Lin |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Annals of translational medicine. 10(23) |
| ISSN: |
2305-5839 |
| Popis: |
Little is known about the role of local therapy in elderly patients with stage IV breast cancer. This study aimed to evaluate the effect of local therapy including surgery and radiotherapy in this kind of population by using the Surveillance, Epidemiology, and End Results (SEER) database.Eligible patients diagnosed between 2010 and 2015 were selected from the SEER database. Baseline characteristics, way of local therapy and survival information were collected for survival and analysis of prognostic factors. Cause-specific survival (CSS) curves were calculated using the Kaplan-Meier (KM) method and compared by the log-rank test. Cox regression and multivariate competing risk analyses were used to analyze prognosis factors.A total of 1,900 patients were enrolled with the median age of 71 (range, 65 to 95) years. The 5-year CSS of patients with surgery was significantly better than that of those who did not (36.5%Elderly patients with stage IV breast cancer can benefit from surgical treatment. This study helps to select the appropriate group for local surgery or radiotherapy according to the personal situation of the elderly to obtain the maximum benefit. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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