Clinical characteristics of coronavirus disease 2019 patients with diarrhea in Daegu
| Autor: | Joon Hyun Cho, Min Kyu Kang, Min Cheol Kim, Jung Gil Park, Kook Hyun Kim, Kyeong Ok Kim, Sung Bum Kim, Tae Nyeun Kim, See Hyung Lee, Byung Ik Jang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Diarrhea
Adult Male medicine.medical_specialty Pneumonia Viral law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Diabetes mellitus Republic of Korea medicine Prevalence Humans SPECIAL COVID-19 Mortality Pandemics Aged Retrospective Studies business.industry Septic shock Hazard ratio COVID-19 Retrospective cohort study Odds ratio Middle Aged medicine.disease Intensive care unit Shock Septic Confidence interval Medicine 030211 gastroenterology & hepatology Original Article Female Radiography Thoracic medicine.symptom business Coronavirus Infections |
| Zdroj: | The Korean Journal of Internal Medicine The Korean Journal of Internal Medicine, Vol 35, Iss 6, Pp 1261-1269 (2020) |
| ISSN: | 2005-6648 1226-3303 |
| Popis: | Background/Aims: Coronavirus disease 2019 (COVID-19) can reportedly cause gastrointestinal symptoms. Therefore, we investigated the clinical characteristics of COVID-19 patients with diarrhea. Methods: We included 118 COVID-19 patients admitted to a single hospital from February 20 to March 31, 2020. Medical records with clinical characteristics, labo ratory data, treatment course, and clinical outcomes were compared based on the presence or absence of diarrhea. Prognostic factors for disease severity and mor tality in COVID-19 were also assessed. Results: Among patients, 54 (45.8%) had diarrhea, whereas seven (5.9%) had only diarrhea. The median age of patients with diarrhea was 59 years (44 to 64), and 22 (40.7%) were male. Systemic steroid use, intensive care unit admission, septic shock, and acute respiratory distress syndrome were less frequent in the diarrhea group than in the non-diarrhea group. No significant differences were observed in total hospital stay and mortality between groups. On multivariate analysis, age (odds ratio [OR], 1.06; 95% confidence interval [CI], 1.01 to 1.12; p = 0.044), diabetes (OR, 3.00; 95% CI, 1.25 to 20.47; p = 0.042), and dyspnea (OR, 41.19; 95% CI, 6.60 to 823.16; p < 0.001) were independent risk factors for septic shock. On Cox regres sion analysis, diabetes (hazard ratio [HR], 4.82; 95% CI, 0.89 to 26.03; p = 0.043) and chronic obstructive pulmonary disease (HR, 16.58; 95% CI, 3.10 to 88.70; p = 0.044) were risk factors for mortality. Conclusions: Diarrhea was present in 45.8% of patients and was a common symp tom of COVID-19. Although patients with diarrhea showed less severe clinical features, diarrhea was not associated with disease severity or mortality. |
| Databáze: | OpenAIRE |
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