Effect of L-Cysteine Hydrochloride, Dl-Alanine, Hydrochloric Acid and Sodium Hydrosulfide on Experimental Polyarthritis of Rats
| Autor: | Verna Wetzel, Leon Libenson |
|---|---|
| Rok vydání: | 1952 |
| Předmět: |
Sodium
chemistry.chemical_element Sodium hydrosulfide Sulfides Pharmacology Arthritis Rheumatoid chemistry.chemical_compound Gold Compounds medicine Animals Immunology and Allergy Cysteine Amino Acids Alanine Arthritis medicine.disease Rats Infectious Diseases DL-Alanine chemistry Biochemistry Rheumatoid arthritis Polyarthritis Hydrochloric Acid |
| Zdroj: | Journal of Infectious Diseases. 91:216-223 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/91.3.216 |
| Popis: | Mouse and rat polyarthritis, induced by pleuropneumonia-like organisms (PPLO), represent a new but important type of disease. This disease has been studied by relatively few investigators. Collier1 and Findlay, Mackenzie and MacCallum2 found that gold compounds exert a preventive action against development of rat polyarthritis. Sabin and Warren3 and Preston, Block and Freyberg4 also reported that such compounds have a curative action on experimental mouse polyarthritis. Although rodent polyarthritis is not identical in its pathology with human rheumatoid arthritis, certain similarities and the beneficial effect of gold in both suggested a common denominator in their etiology, and also the possibility that, through chemotherapeutic trials in animals, other agents could be found more effective and less toxic than the |
| Databáze: | OpenAIRE |
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