Fulminant inflammatory demyelination presenting as stroke‐in‐evolution in an elderly subject
| Autor: | Isabella Canavero, Sabrina Ravaglia, Elisa Coloberti, Simone Sacco, Lisa Maria Farina, Anna Simoncelli, Giuseppe Micieli, Anna Pichiecchio, Ilaria Callegari |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
tumefactive demyelinating lesions medicine.medical_treatment Fulminant Neuroimaging Neurosciences. Biological psychiatry. Neuropsychiatry 050105 experimental psychology Stroke in evolution 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Commentaries inflammatory demyelinating disorders medicine Humans 0501 psychology and cognitive sciences fulminant inflammatory demyelination Demyelinating Disorder Intensive care medicine Stroke Pathological Aged business.industry ADEM 05 social sciences Stroke mimics Brain Immunosuppression medicine.disease Encephalitis Female business 030217 neurology & neurosurgery Demyelinating Diseases RC321-571 |
| Zdroj: | Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021) Brain and Behavior |
| ISSN: | 2162-3279 |
| Popis: | Background Fulminant inflammatory demyelination is a possible presentation of inflammatory demyelinating disorders, thus representing a potential stroke mimic especially in younger patients. Aims of the study To describe clinical and diagnostic pitfalls in a case of fulminant inflammatory demyelination presenting with stroke‐like symptoms in an elderly patient. Methods Case report and case‐based review of the literature. Results A 67‐year‐old woman, who accessed the emergency room as suspect stroke for hyperacute onset of rapidly worsening speech impairment and drowsiness, was later diagnosed with a huge brain inflammatory demyelination. Clinical, laboratory, and neuroimaging tests did not allow to put a more specific diagnosis. Due to the rapidly deteriorating course, she received immunosuppression with benefit. Conclusion This report is meant to highlight the diagnostic challenges connected with fulminant inflammatory demyelination, which sometime can resemble a stroke‐in evolution and appear clinically unfitting for inclusion in any specific pathological entities within the broad‐spectrum of inflammatory demyelinating disorders. Fulminant inflammatory demyelination represents a possible presentation of inflammatory demyelinating disorders. Here we describe a case affecting a 67 year‐old woman, who accessed the emergency room for hyperacute onset of rapidly worsening speech impairment and drowsiness. This report is meant to highlight the diagnostic challenges connected with fulminant inflammatory demyelination, which sometime can resemble a stroke‐in evolution and appear clinically unfitted for inclusion in any specific pathological entities within the broad spectrum of inflammatory demyelinating disorders. |
| Databáze: | OpenAIRE |
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