Neuropharmacological and cochleotoxic effects of styrene. Consequences on noise exposures
| Autor: | Pierre Campo, Chantal Cour, Aurélie Thomas, Céline Brochard, Frédéric Cosnier, Thomas Venet |
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| Rok vydání: | 2014 |
| Předmět: |
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medicine.medical_specialty Hearing loss Central nervous system Audiology Toxicology Impulse noise Styrene Cellular and Molecular Neuroscience chemistry.chemical_compound Developmental Neuroscience otorhinolaryngologic diseases Animals Medicine Acoustic reflex Sound pressure Organ of Corti business.industry Reflex Acoustic Rats Hair Cells Auditory Outer Noise medicine.anatomical_structure Hearing Loss Noise-Induced chemistry Solvents sense organs medicine.symptom business |
| Zdroj: | Neurotoxicology and Teratology. 44:113-120 |
| ISSN: | 0892-0362 |
| DOI: | 10.1016/j.ntt.2014.05.009 |
| Popis: | Occupational noise exposure can damage workers' hearing, particularly when combined with exposure to cochleotoxic chemicals such as styrene. Although styrene-induced cochlear impairments only become apparent after a long incubation period, the pharmacological impact of styrene on the central nervous system (CNS) can be rapidly measured by determining the threshold of the middle-ear acoustic reflex (MER) trigger. The aim of the study was to evaluate the effects of a noise (both continuous and impulse), and a low concentration of styrene [300ppm |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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