The effect of ABO blood group on COVID-19 in pregnancy
| Autor: | Sulistyowati, Sri, Anggraini, Nutria Widya Purna, Soetrisno, Soetrisno, Yuliantara, Eric Edwin, Respati, Supriyadi Hari, Bachnas, Muhammad Adrianes, Prabowo, Wisnu, Nurinasari, Hafi, Pramelita, Dympna, Setiyawati, Dewi, Sujana, Metharisa, Firmansyah, Aldi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Jurnal Kedokteran dan Kesehatan Indonesia; JKKI, Vol 12, No 3, (2021); 233-241 JKKI : Jurnal Kedokteran dan Kesehatan Indonesia; JKKI, Vol 12, No 3, (2021); 233-241 |
| ISSN: | 2527-2950 2085-4145 |
| DOI: | 10.20885/jkki.vol12.iss3.art6 |
| Popis: | Background: The COVID-19 virus has spread throughout the world and has been declared as a global pandemic by WHO. Some population groups are more susceptible to COVID-19, and one of them is pregnant women. Pregnancy increases risks of the COVID-19, especially thrombotic complications. The SARS-CoV-2 infection may vary widely from asymptomatic to severe infection. Some studies have shown that ABO blood group can be a marker of susceptibility to some disease progression. Objective:This study aims to investigate relationships between the ABO blood group, the COVID-19 infection and its complications in pregnant women at Dr. Moewardi Hospital, Surakarta.Methods: This study was an observational analytic study with a cross-sectional study design involving 40 pregnant women infected with COVID-19 at Dr. Moewardi Hospital, Surakarta. COVID-19 PCR swabs on the women were administered on their oropharynx and nasopharynx, and laboratory examination of the ABO blood group in all samples was performed. Comparative data distribution of blood groups in the population and the global population distribution were calculated by Chi Square Goodness of Fit. Comparative data between ABO blood group distributions, blood parameters and complications (respiratory, thrombotic, other infections, and death) were calculated by Chi square test and then by One-Way ANOVA. Next, correlation tests for the complications of the blood group and the ages applied a multinomial regression.Results: There were significant differences of thrombotic complications on the blood group of pregnant women infected with COVID-19 (p=0.027). Blood type B significantly tended to experience thrombotic complications when compared to other blood groups (p=0.022).Conclusion: The ABO blood group could affect the complication levels in the pregnant women infected with the COVID 19. Background: The COVID-19 virus infection has spread throughout the world and has been declared as a global pandemic by WHO. Some population groups were more susceptible to COVID-19 infection, one of them was pregnant women. Pregnancy increases the risk of COVID-19, especially thrombotic complications. The clinical course of SARS-CoV-2 infection may varies widely from asymptomatic to severe clinical condition. Several studies have shown that ABO blood type could be a marker of susceptibility to disease progression. In this study, we investigated the relationship between ABO blood grouping and COVID-19 infection and its complications in pregnant women at Dr. Moewardi General Hospital Surakarta.Methods: This study was an observational analytic study with a cross-sectional study design involving 40 pregnant women patients suspected of infected COVID-19 at Dr. Moewardi General Hospital, Surakarta. A COVID-19 PCR swab was performed on oropharynx and nasopharynx and laboratory examination of ABO blood group in all samples. Comparative data distribution of blood groups in the study population with the global population distribution was calculated using Chi Square Goodness of Fit. Comparative data between ABO blood group distribution with blood parameters and complications (respiratory, thrombotic, other infections, and death) were calculated by Chi square test for categorical, and continuous with and One-Way ANOVA. The correlation test for complications of blood group and age using multinomial regression.Results: There were significant difference in thrombotic complications and the blood group of pregnant women infected with COVID-19 (p=0.027). Blood type B was significantly more likely to experience thrombotic complications when compared to other blood groups (p=0.022).Conclusion: ABO blood type affects the level of complications caused by COVID 19 infection in pregnant women |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|