Spatiotemporal Heterogeneity of Zika Virus Transmission in Indonesia: Serosurveillance Data from a Pediatric Population
| Autor: | William A. Hawley, Chairin Nisa Ma'roef, Ann M. Powers, Khin Saw Aye Myint, Ronald Rosenberg, Elizabeth Jane Soepardi, Edison Johar, Sri Rezeki Hadinegoro, Amin Soebandrio, Benediktus Yohan, Alain Bouckenooghe, R. Tedjo Sasmono, Paul Pronyk |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
biology
Transmission (medicine) 030231 tropical medicine Disease Articles biology.organism_classification Asymptomatic Virology Serology Zika virus Geographic distribution 03 medical and health sciences 0302 clinical medicine Infectious Diseases medicine Seroprevalence Parasitology medicine.symptom Pediatric population |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | The presence of Zika virus (ZIKV) in Indonesia has been recognized since the 1970s, but its transmission dynamics there have been poorly understood. To understand more fully the geographic distribution and burden of ZIKV infection, we performed retrospective serological tests on specimens collected from asymptomatic children age 5 to 9 years old living at 30 sites in 14 provinces. Of 870 serum samples tested, 9.2% were found to be positive for anti-ZIKV antibodies, as confirmed by plaque reduction neutralization assays. This was the same overall prevalence reported previously for 1- to 4-year-old children collected at the same sites at the same time. Together with geographic differences in seroprevalence between the age groups, these data suggest that, although ZIKV might be endemic in Indonesia, its occurrence has been focal and episodic. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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