Risk factors for Blastocystis infection in HIV/AIDS patients with highly active antiretroviral therapy in Southwest China
| Autor: | Fen-Yan Kang, Lan-Lan Geng, Jia-Xu Chen, Li-Guang Tian, Shunxian Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty China Interaction Short Report Blastocystis Infections Stool specimen lcsh:Infectious and parasitic diseases Acquired immunodeficiency syndrome (AIDS) Risk Factors Internal medicine Antiretroviral Therapy Highly Active medicine Prevalence Humans lcsh:RC109-216 Risk factor Virus load Blastocystis Acquired Immunodeficiency Syndrome biology business.industry Coinfection lcsh:Public aspects of medicine Public health Public Health Environmental and Occupational Health lcsh:RA1-1270 General Medicine Middle Aged medicine.disease biology.organism_classification Antiretroviral therapy Co-infection Infectious Diseases Cross-Sectional Studies Tropical medicine HIV/AIDS Female business |
| Zdroj: | Infectious Diseases of Poverty Infectious Diseases of Poverty, Vol 8, Iss 1, Pp 1-8 (2019) |
| ISSN: | 2049-9957 2095-5162 |
| Popis: | Background Blastocystis is a widespread zoonotic protozoan of mammalian species, especially in HIV/AIDS individuals. The aim of this study was to analyze the prevalence and risk factors related with Blastocystis infection among HIV/AIDS patients in Southwest China. Methods The cross-sectional study was performed in 311 HIV/AIDS cases in Tengchong City, Yunnan Province from July 2016 to March 2017. For each subject, stool specimen was collected to detect the Blastocystis, and the blood sample was used to detect HIV virus load and CD4+ T cell count, in addition, structured questionnaire was used to collect the basic information and risk factors. Findings The result showed that the detection rate of Blastocystis was 3.86% (95% CI: 2.22–6.62) among HIV/AIDS patients. Both raising animal (OR = 12.93, 95% CI: 1.54–108.36) and drinking un-boiled water (OR = 8.17, 95% CI: 1.76–37.90) were risk factors for Blastocystis infection in HIV/AIDS individuals. In addition, the interaction of CD4+ T cell count and HIV virus load was also contribution to Blastocystis infection (P = 0.007). Conclusions A high prevalence of Blastocystis infection was found in HIV/AIDS patients in Tengchong. Poor hygienic habits, the interaction of HIV virus load and CD4+ T cell count were identified as main risk factors for infection. These results will help us to develop efficient control strategies to intervene with and prevent the occurrence of Blastocystis among HIV-infected individuals. |
| Databáze: | OpenAIRE |
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