Neutralizing antibody in nasal secretions of chickens following administration of avian infectious bronchitis virus
| Autor: | H. C. Holmes |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Virus Cultivation
Coronaviridae Infectious bronchitis virus Mucous membrane of nose Chick Embryo Antibodies Viral Kidney Vaccines Attenuated Virus Microbiology Lactones Heterocyclic Compounds Neutralization Tests Culture Techniques Virology otorhinolaryngologic diseases Animals Bronchitis Neutralizing antibody Administration Intranasal Poultry Diseases Antiserum biology Immune Sera Viral Vaccines General Medicine biology.organism_classification Nasal Mucosa Virus Diseases Antibody Formation Immunology biology.protein Immunization Nasal administration Propionates Avian infectious bronchitis virus Antibody Chickens |
| Zdroj: | Archiv f�r die gesamte Virusforschung. 43:235-241 |
| ISSN: | 1432-8798 0304-8608 |
| DOI: | 10.1007/bf01250418 |
| Popis: | Intranasal instillation of live infectious bronchitis (IB) virus resulted in low levels of neutralizing antibody in the nasal secretions of chickens. However, when preceded by administration of β-propriolactone-inactivated or live homologous virus, markedly elevated levels of nasal antibody were found, particularly in the latter case. The origin of this nasal antibody is discussed. Transudation from serum was largely discounted as it was shown that only negligible amounts of antibody could be detected in nasal washings from birds given IB, antiserum intravenously—local synthesis was considered the more likely origin. |
| Databáze: | OpenAIRE |
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