Airborne Food Allergen and Aeroallergen Levels in Health Care Settings: An Unaccounted for but Potentially Relevant Source of Exposure?
| Autor: | Luís Delgado, F. Castro Mendes, Inês Paciência, Carla Viegas, Mariana Leal, Mariana Farraia, Ana S. P. Moreira, J. Cavaleiro Rufo |
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| Přispěvatelé: | Instituto de Saúde Pública da Universidade do Porto |
| Rok vydání: | 2021 |
| Předmět: |
Aeroallergens
Immunology Indoor exposure Healthcare center Dogs Project nº 23222 (02/SAICT/2016) Allergic disease Animals Humans Immunology and Allergy Medicine Airborne food allergens Mites Occupational health business.industry Health care centers Dust Occupational exposure Allergens Asthma Air Pollution Indoor Healthcare settings Cats Project nº 30193 (02/SAICT/2017 business Delivery of Health Care Humanities |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| ISSN: | 1018-9068 |
| DOI: | 10.18176/jiaci.0623 |
| Popis: | Background and objective: Exposure to airborne allergens of biological origin is associated with the development and exacerbation of allergic asthma and rhinitis. Assessment of allergen exposure in health care facilities may improve monitoring of hygiene and surveillance of specific allergens that can cause symptoms in sensitized persons. Objective: To assess concentrations of airborne food and aeroallergens in various health care settings in Portugal. Methods: Dust was vacuumed from primary health care centers in Lisbon and from the emergency department, day hospital, internal medicine ward, operating room, and outpatient clinic of a university central hospital in Porto. Samples were sieved, weighed, and extracted, and concentrations of Nbos d 5, Cor a 9, Gal d 2, Ara h 3, Ara h 6, Der p 1, Fel d 1, Can f 1, Bla g 2, Alt a 1, and Phl p 5 were determined using a multiplex array for allergens (MARIA). Results: All airborne food and aeroallergens were found in at least 1 sampled area, except for Alt a 1. Levels of Der p 1 and Fel d 1 ranged from 13.0 μg/g to 971.0 μg/g and from 7.0 μg/g to 4618.8 μg/g, respectively. Higher levels of food allergens were found in the emergency department (Nbos d 5, 16 034.0 μg/g; and Cor a 9, 10 649.5 μg/g). Conclusions: Except for the operating room, exposure levels for dust mite and cat and dog dander in health care facilities were above the values associated with sensitization and allergic asthma or rhinitis symptoms in sensitized persons. The study was funded by the ExPOSE – Establishing protocols to assess occupational exposure to microbiota in clinical settings project (02/SAICT/2016 – Project no. 23222), by Project NORTE-01-0145-FEDER-000010 – Health, Comfort and Energy in the Built Environment (HEBE), and cofunded by Programa Operacional Regional do Norte (NORTE2020), through Fundo Europeu de Desenvolvimento Regional (FEDER), and EXALAR 21, a project funded by FEDER/FNR and by Fundação para a Ciência e Tecnologia (EXALAR 21 02/SAICT/2017 - Project no. 30193). |
| Databáze: | OpenAIRE |
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