Intraoperative indocyanine green fluorescence guidance for excision of nonpalpable breast cancer
Autor: | Jintao Liu, Meng Tong, Wenbin Guo |
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Jazyk: | angličtina |
Předmět: |
Adult
Indocyanine Green medicine.medical_specialty Lesion excision Intraoperative excision Breast Neoplasms 030230 surgery Mastectomy Segmental Fluorescence 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Breast cancer Surgical oncology medicine Humans Nonpalpable breast cancer Aged Fluorescent Dyes Retrospective Studies business.industry Research Carcinoma Ductal Breast Indocyanine green fluorescence imaging Margins of Excision Retrospective cohort study Middle Aged medicine.disease Carcinoma Intraductal Noninfiltrating chemistry Surgery Computer-Assisted Oncology 030220 oncology & carcinogenesis Female Surgery Radiology Ultrasonography Mammary business Indocyanine green Indocyanine green fluorescence |
Zdroj: | World Journal of Surgical Oncology |
ISSN: | 1477-7819 |
DOI: | 10.1186/s12957-016-1014-2 |
Popis: | Background Different techniques have been used for the guidance of nonpalpable breast cancer (NBC), but none of them has yet achieved perfect results. The aim of this study was to evaluate the feasibility of indocyanine green (ICG) fluorescence-guided nonpalpable breast cancer lesion excision (IFNLE), to introduce an alternative technique. Methods The data about 56 patients with preoperatively diagnosed NBCs operated with the help of intraoperative IFNLE between November of 2010 and September of 2014 were retrospectively analyzed. Results ICG fluorescence localized all lesions at surgery. Re-excision due to positive resection margins was necessary in two patients (3.6 %; 2/56) with ductal carcinoma in situ (DCIS) at the surgical margins. Mastectomy was necessary in one patient (1.8 %; 1/56) due to multifocal invasive carcinoma. The mean volume of the excised tissue was 38.2 ± 16.5 cm3. Conclusions IFNLE is a technically applicable and clinically acceptable procedure whenever a breast cancer needs image-guided excision. |
Databáze: | OpenAIRE |
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