Etiology and management of hypofibrinogenemia of pregnancy

Autor: C. Paul Hodgkinson, J. H. Luzadre, R. R. Margulis
Rok vydání: 1954
Předmět:
Zdroj: Journal of the American Medical Association. 154(7)
ISSN: 0002-9955
Popis: Incoagulable blood as the result of hypofibrinogenemia is an obstetric syndrome of unusual clinical significance. Death from unmanageable hemorrhage may be the penalty. Prompt recognition of the condition and institution of appropriate therapy are obligations of the obstetrician. Hypofibrinogenemia is known to occur superimposed upon two complications of pregnancy. The first and most widely recognized complication is abruptio placentae. The second is prolonged retention of a dead fetus in an Rh-isosensitized mother. Incoagulable blood from a deficiency in circulating fibrinogen is the outstanding pathological characteristic common to both conditions. Detailed analysis of cases discloses possible differences in causes and clinical manifestations. ABRUPTIO PLACENTAE TYPE Case 1.— A 26-year-old woman, para 1, gravida 2, was admitted to Henry Ford Hospital at 12:30 a. m., Dec. 4, 1952, with toxemia and clinical symptoms suggestive of abruptio placentae. Labor had begun at 9:30 p. m. on Dec. 3. Two hours after the patient
Databáze: OpenAIRE