Modification of Intestinal Secretion in Experimental Cholera
| Autor: | Curran Pf, Schultz Sg, Norris Ht |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Diarrhea
Malabsorption Ileum Sodium Chloride Pharmacology Models Biological Bacterial Proteins Chlorides Cholera Maintenance therapy Intestinal mucosa In vivo medicine Animals Immunology and Allergy Vibrio Dehydration Intestinal Secretions Chemistry Sodium medicine.disease Acetazolamide Intestinal secretion Bicarbonates Glucose Infectious Diseases medicine.anatomical_structure Intestinal Absorption Immunology Potassium Female Rabbits Rice water stool |
| Zdroj: | Journal of Infectious Diseases. 119:117-125 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/119.2.117 |
| Popis: | Adequate treatment for cholera has been devised, but it consists primarily of intravenous administration of large amounts of fluid to replace the intestinal losses of salt and water. It would be of considerable benefit to develop alternative or supplementary methods that would reduce the amount of fluid necessary for initial and maintenance therapy, but such an approach requires a better understanding of the pathogenesis of this disease. Recent work has suggested that study of rabbit ileum may provide some additional insight into the problem. In vivo loops of this tissue respond to various choleragenic materials by production of fluid that is quite similar in electrolyte content [1-3] to that observed in the rice water stool of cholera patients [4]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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