Updating Zika Diagnostic Methods: The Point-of-Care Approach
| Autor: | Mirna Burciaga-Flores, Marissa Reyes-Galeana, Darwin Elizondo-Quiroga, Abel Gutiérrez-Ortega, Tanya A. Camacho-Villegas |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Microcephaly Diagnostic methods biology Zika Virus Infection business.industry Transmission (medicine) Point-of-Care Systems General Medicine medicine.disease biology.organism_classification Dengue fever Zika virus Humans Medicine business Horizontal transmission Point of care Congenital blindness |
| Zdroj: | Revista de investigaci�n Cl�nica. 72 |
| ISSN: | 0034-8376 |
| DOI: | 10.24875/ric.20000160 |
| Popis: | Zika virus (ZIKV) has gained great importance worldwide since the past epidemic that occurred in 2015 in Brazil. Early identification of ZIKV is critical to minimize transmission and prevents potentially devastating consequences, including microcephaly in neonates of infected women, congenital blindness, or Guillain-Barré Syndrome. However, this is not an easy task, considering that approximately 80% of ZIKV infection cases are asymptomatic or oligosymptomatic, there are diverse modes of transmission (vertical transmission is through vectors and horizontal transmission through blood, saliva, semen, and urine from infected people), and the fact that ZIKV has a high identity percentage with other cocirculating Flaviviruses such as dengue. Here, we review ZIKV diagnostic methods, with special emphasis on the development of point-of-care diagnostic assays, since these devices commonly have two important advantages: they provide prompt screening and are affordable. |
| Databáze: | OpenAIRE |
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