Effect of exercise training on functional capacity and body composition in myotonic dystrophy type 2 patients
| Autor: | Evangelia Kararizou, Gerasimos Terzis, Spyridon Methenitis, Argyris G. Toubekis, G.K. Papadimas, Sophia Xirou, Eleni Kontou, Gregory C. Bogdanis, Constantinos Papadopoulos |
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| Rok vydání: | 2021 |
| Předmět: |
Male
musculoskeletal diseases 0301 basic medicine medicine.medical_specialty Physiology Myotonic dystrophy type 2 Walking 030105 genetics & heredity 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Physiology (medical) medicine Humans Myotonic Dystrophy Aerobic exercise Muscle Strength Muscle Skeletal Exercise Aged Aged 80 and over Bone mineral Muscle Weakness Hand Strength business.industry Muscle weakness Middle Aged Myotonia medicine.disease Blood pressure Physical Fitness Ambulatory Body Composition Lean body mass Physical therapy Female Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Muscle & Nerve. 63:477-483 |
| ISSN: | 1097-4598 0148-639X |
| DOI: | 10.1002/mus.27156 |
| Popis: | Background Myotonic dystrophy type 2 (DM2) is a neuromuscular disorder characterized by myotonia and muscle weakness, with no medical treatment to prevent a decline in decline. It is unknown whether exercise training is effective in DM2. The aim of this study was to investigate the effect of exercise training on functional capacity and body composition in these patients. Methods Body composition and functional capacity were evaluated at the beginning (T1) and end (T2) of a 12 wk control period, and again after 16 wk of exercise training (T3) in 10 patients. Results No changes were recorded after the control period. Handgrip strength, 5× sit to stand, timed up and go, 6 min walk distance, lean body mass (LBM), and bone mineral density (BMD) increased while arterial pressure decreased after training. Conclusions These results suggest that supervised exercise training improves functional capacity, LBM, and BMD in ambulatory DM2 patients. |
| Databáze: | OpenAIRE |
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