Storiform collagenoma (sclerotic fibroma) of the oral mucosa
| Autor: | T. Bates, D. Zardo, Ross Elledge, B. Nandra, Sat Parmar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Skin Neoplasms Fibroma Fibrous tissue Oral cavity 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Eosinophilic medicine Humans PTEN Oral mucosa Head and neck biology business.industry Mouth Mucosa medicine.disease stomatognathic diseases medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis biology.protein Sclerotic fibroma Surgery Collagen Oral Surgery Hamartoma Syndrome Multiple business Storiform collagenoma |
| Zdroj: | British Journal of Oral and Maxillofacial Surgery. 58:231-233 |
| ISSN: | 0266-4356 |
| Popis: | Storiform collagenoma (also called sclerotic fibroma) is uncommon, occurs as a cutaneous fibrous neoplasm, and is particularly rare in mucosal tissue in the head and neck. We describe an unexpected diagnosis in the oral cavity. Histopathological examination showed a proliferation of fibrous tissue, which was well circumscribed but unencapsulated, with thick laminated bundles of eosinophilic collagen that exhibited a storiform or "whorled" pattern. First described by Weary et al in 1972, storiform collagenoma is a marker for Cowden's disease or PTEN hamartoma tumour syndrome. Identification of other synchronous lesions should prompt chromosomal analysis for a mutation in the PTEN gene on chromosome 10q23. |
| Databáze: | OpenAIRE |
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