The processing of animacy information is disrupted as a function of callous-unemotional traits in youth with disruptive behavior disorders
| Autor: | Soonjo Hwang, Stephen Sinclair, Harma Meffert, Zachary T. Nolan, Elizabeth Penner, Christopher J. Adalio, Laura C. Thornton, Stuart F. White, R. James R. Blair |
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| Rok vydání: | 2017 |
| Předmět: |
Conduct Disorder
Male 050103 clinical psychology Adolescent Cognitive Neuroscience Asociality Emotions lcsh:Computer applications to medicine. Medical informatics Amygdala lcsh:RC346-429 Developmental psychology 03 medical and health sciences 0302 clinical medicine medicine Humans 0501 psychology and cognitive sciences Radiology Nuclear Medicine and imaging Child lcsh:Neurology. Diseases of the nervous system Temporal cortex Callous unemotional Disruptive behavior fMRI 05 social sciences Regular Article medicine.disease Oppositional Defiant Disorder medicine.anatomical_structure Neurology Attention Deficit and Disruptive Behavior Disorders Conduct disorder lcsh:R858-859.7 Female Neurology (clinical) Psychology Animacy 030217 neurology & neurosurgery Social cognitive theory |
| Zdroj: | NeuroImage : Clinical NeuroImage: Clinical, Vol 16, Iss, Pp 498-506 (2017) |
| ISSN: | 2213-1582 |
| Popis: | Atypical amygdala responses to emotional stimuli have been consistently reported in youth with Disruptive Behavior Disorders (DBDs; Conduct Disorder/Oppositional Defiant Disorder). However, responding to animacy stimuli has not been systematically investigated. Yet, the amygdala is known to be responsive to animacy stimuli and impairment in responsiveness to animacy information may have implications for social cognitive development. Twenty-nine youth with DBDs and 20 typically developing youth, matched for IQ, age (Mage = 14.45, SD = 2.05) and gender, completed a dot probe task during fMRI. Stimuli consisted of negative/faces, negative/objects, neutral/faces and neutral/objects images. Youth with DBDs, relative to typically developing youth, showed: i) reduced amygdala and lateral temporal cortex responses to faces relative to objects. Moreover, within the group of youth with DBDs, increasing callous-unemotional traits were associated with lesser amygdala responses to faces relative to objects. These data suggest that youth with DBDs, particularly those with high levels of CU traits exhibit dysfunction in animacy processing in the amygdala. This dysfunction may underpin the asociality reported in these youth. Highlights • Animacy processing within the amygdala is a critical component of social cognition. • Youth with DBDs had reduced responses to faces compared to objects in amygdala. • CU traits were associated with reduced amygdala responses to faces. • Youth with DBDs, particularly those with CU exhibit problems in animacy processing. |
| Databáze: | OpenAIRE |
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