Cardiovascular Risk Factors in Hemodialysis Patients: Results from Baseline Data of Kaleidoscopic Approaches to Patients with End-stage Renal Disease Study
| Autor: | Motoyuki Nakamura, Kazuyoshi Itai, Masaki Ohsawa, Karen Kato, Tomoaki Fujioka, Ryuichiro Konda, Akira Okayama, Toshiyuki Onoda |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Epidemiology Cross-sectional study medicine.medical_treatment Population Comorbidity End stage renal disease Diabetic nephropathy Japan Renal Dialysis Risk Factors Surveys and Questionnaires Internal medicine Diabetes mellitus Prevalence Humans Medicine education Aged Aged 80 and over education.field_of_study biology business.industry C-reactive protein General Medicine Middle Aged medicine.disease Surgery C-Reactive Protein Cross-Sectional Studies Blood pressure Cardiovascular Diseases biology.protein Kidney Failure Chronic Female Original Article Hemodialysis business the KAREN Study |
| Zdroj: | Journal of Epidemiology |
| ISSN: | 1349-9092 0917-5040 |
| DOI: | 10.2188/jea.15.96 |
| Popis: | BACKGROUND: The prevalence of cardiovascular risk factors and the prevalence of comorbidities in adult hemodialysis patients in Japan are not fully understood.METHODS: In "Kaleidoscopic Approaches to Patients with End-stage Renal Disease Study" (The KAREN Study, 2003), trained research stuff examined 1,214 adult hemodialysis patients (mean age, 61.2 years; 779 males and 435 females) of 1,506 patients in northern areas of Iwate Prefecture. Cardiovascular risk factors and the prevalence of comorbidities in hemodialysis patients were compared with those in the general population using direct age-adjustment methodology and standardized morbidity ratios (SMRs).RESULTS: In hemodialysis patients, common causes of end-stage renal disease were chronic glomerulonephritis (29.8%), diabetic nephropathy (24.5%), and other diseases. Prevalence and SMR of myocardial infarction were 5% and 9.6, respectively, and those of stroke were 13% and 5.7. The prevalences of hypertension and diabetes mellitus were 87% and 29%, respectively. Mean systolic blood pressure and mean diastolic blood pressure were 155 mmHg and 85 mmHg, respectively. Mean levels of total serum cholesterol, high-density lipoprotein cholesterol, and albumin in patients with end-stage renal disease were lower than those of the general population (160.6 vs. 203.3 mg/dL, 48.5 vs. 59.7 mg/dL, and 3.7 vs. 4.4 g/dL, respectively). Mean levels of C-reactive protein were higher than those of the general population (3.80 vs. 1.16 mg/L).CONCLUSION: Hemodialysis patients have a high prevalence of cardiovascular risk factors and comorbidities. Levels of nutrition-related markers were lower, and C-reactive protein levels were higher, in hemodialysis patients than in the general population.J Epidemiol 2005 ;15: 96-105. |
| Databáze: | OpenAIRE |
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