Nanotechnology Development and Utilization: A Primer for Diagnostic and Interventional Radiologists
| Autor: | Daniel P. Link, Derek S. Vien, Wayne L. Monsky |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Diagnostic Imaging
medicine.medical_specialty Nanotechnology education Multifunctional nanoparticles Contrast Media Nanotechnology Injections Intralesional Radiology Interventional Imaging modalities Drug Delivery Systems Neoplasms Animals Humans Medicine Radiology Nuclear Medicine and imaging Medical physics Tumor imaging Drug Carriers business.industry Financing Organized Molecular Imaging Novel agents Molecular targets Nanoparticles Molecular imaging Radiology business |
| Zdroj: | RadioGraphics. 31:1449-1462 |
| ISSN: | 1527-1323 0271-5333 |
| DOI: | 10.1148/rg.315105238 |
| Popis: | The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles. |
| Databáze: | OpenAIRE |
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