Bilateral internal auditory canal gangliogliomas mimicking neurofibromatosis Type II
| Autor: | Seth F Oliveria, Stephen B. Lewis, Saeed S. Sadrameli, Kristopher G Hooten, Anthony T. Yachnis, Shashank Gandhi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
tumors
medicine.medical_specialty Case Report Ganglioglioma 03 medical and health sciences cerebellar-pontine angle 0302 clinical medicine internal auditory canal Vertigo otorhinolaryngologic diseases medicine gangliogliomas Neurofibromatosis medicine.diagnostic_test biology business.industry Cranial nerves Magnetic resonance imaging Bilateral Cerebellopontine angle biology.organism_classification medicine.disease Surgery 030220 oncology & carcinogenesis Neurology (clinical) Differential diagnosis medicine.symptom business 030217 neurology & neurosurgery Tinnitus |
| Zdroj: | Surgical Neurology International |
| ISSN: | 2152-7806 |
| DOI: | 10.4103/2152-7806.180300 |
| Popis: | Background Gangliogliomas are rare low grade, typically well-differentiated, tumors that are composed of mature ganglion cells and neoplastic glial cells. These tumors can appear at virtually any location along the neuroaxis but classically occur in the temporal lobe of young patients. In a small number of cases, gangliogliomas have presented as masses in the brainstem or involving cranial nerves. With the exception of vestibular schwannomas, bilateral tumors in the region of the internal auditory canal (IAC) or cerebellopontine angle (CPA) are exceedingly rare. Case description We report a case of a 58-year-old male who presented with hearing loss, tinnitus, and vertigo. Initial magnetic resonance imaging revealed bilateral nonenhancing IAC/CPA tumors. Based on this finding, a presumptive diagnosis of neurofibromatosis Type II was made, which was initially managed conservatively with close observation. He returned for follow-up with worsening vertigo and tinnitus, thus prompting the decision to proceed with surgical resection of the symptomatic mass. Intriguingly, pathological study demonstrated a WHO Grade I ganglioglioma. Description We report a case of a 58-year-old male who presented with hearing loss, tinnitus, and vertigo. Initial magnetic resonance imaging revealed bilateral nonenhancing IAC/CPA tumors. Based on this finding, a presumptive diagnosis of neurofibromatosis Type II was made, which was initially managed conservatively with close observation. He returned for follow-up with worsening vertigo and tinnitus, thus prompting the decision to proceed with surgical resection of the symptomatic mass. Intriguingly, pathological study demonstrated a WHO Grade I ganglioglioma. Conclusion This is the first reported case of bilateral IAC/CPA gangliogliomas. When evaluating bilateral IAC/CPA lesions with unusual imaging characteristics, ganglioglioma should be included in the differential diagnosis. |
| Databáze: | OpenAIRE |
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