| Autor: |
Chiche, Aurélie, Di-Cicco, Amandine, Sesma-Sanz, Laura, Bresson, Laura, Grange, Pierre De La, Glukhova, Marina, Faraldo, Marisa, Marie-Ange Deugnier |
| Rok vydání: |
2019 |
| DOI: |
10.6084/m9.figshare.7635044 |
| Popis: |
Figure S1. Molecular characteristics of the luminal subsets isolated from control and K5Cre;Trp53F/F adult virgin mice using ICAM-1. (a) Heat map showing hierarchical clustering of the 7 Lu-pos and Lu-neg cell samples analyzed. A total of 1115 genes with a minimal intensity level of 7 displayed a fold-change ≥ 1.5. (b) Expression heat map of the top 100 modulated genes. (c) Venn diagram showing the number of activated p53 target genes differentially expressed in Lu-pos and Lu-neg cell populations. (d) Relative expression levels of p53 target genes in Lu-pos cells isolated from control and K5Cre;Trp53F/F mutant adult virgin mice. The qPCR data are shown as mean ratios ± SEM between gene expression levels in mutant and control Lu-pos cells from at least 3 separate preparations. *p ≤ 0.05, **p ≤ 0.01. (PDF 8195 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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