The association between pre-pregnancy body mass index, perinatal depression and maternal vitamin D status: Findings from an Australian cohort study
Autor: | Rati Jani, Monica Yuri Takito, Cathy Knight-Agarwal, Michael Bloom |
---|---|
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
obesity International Journal of Women's Health Overweight vitamin D deficiency 03 medical and health sciences 0302 clinical medicine Maternity and Midwifery Vitamin D and neurology Medicine overweight 030212 general & internal medicine Depression (differential diagnoses) Original Research DEPRESSÃO 030219 obstetrics & reproductive medicine business.industry Obstetrics pregnancy nutrition Obstetrics and Gynecology Retrospective cohort study medicine.disease Oncology depression medicine.symptom business Body mass index Perinatal Depression Cohort study |
Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP International Journal of Women's Health |
Popis: | Rati Jani,1 Catherine R Knight-Agarwal,1 Michael Bloom,2 Monica Yuri Takito3 1The University of Canberra, School of Clinical Sciences, Faculty of Health, Canberra, ACT, Australia; 2Northern Sydney Local Area Health District, Sydney, NSW, Australia; 3School of Physical Education and Sport, The University of Sao Paulo, Sao Paulo, BrazilCorrespondence: Rati JaniThe University of Canberra, School of Clinical Sciences, Faculty of Health, Canberra, ACT, AustraliaTel +61 407806663Fax +61 2 6201 5040Email rati.jani@canberra.edu.auPurpose: This study aimed to assess the relationship between early-pregnancy Body Mass Index (BMI), perinatal depression risk and maternal vitamin D status.Patients and Methods: A retrospective cohort study from 2013 to 2017 was undertaken involving 16,528 birth events in the Australian Capital Territory. Multivariate binary logistic regression was conducted using the forced entry method. Mediation of the association between maternal early-pregnancy BMI and perinatal depression risk by vitamin D status was also tested.Results: Adjusted logistic regression models found that high maternal early-pregnancy BMI was associated with increased risk of developing perinatal depression (AOR 1.421; 95% CI, 1.191, 1.696) as well as increased odds of being vitamin D deficient (AOR 1.950; 95% CI; 1.735, 2.191). In comparison to women with low perinatal depression risk, women with high perinatal depression risk had increased odds of being vitamin D deficient (AOR 1.321; 95% CI, 1.105, 1.579). Maternal early-pregnancy BMI was a weak significant predictor of perinatal depression risk after including vitamin D as a mediator, consistent with partial mediation, Path C: B=0.016 (95% CI 1.003, 1.030), p= 0.02. Path C´: B=0.014 (95% CI 1.001, 1.028), p= 0.04.Conclusion: In line with current Australian recommendations, women with high early-pregnancy BMI should be screened for both perinatal depression risk and vitamin D deficiency, with referral to relevant support services when indicated.Keywords: overweight, obesity, pregnancy nutrition, depression |
Databáze: | OpenAIRE |
Externí odkaz: |