Protein deficiency in primates. IV. Pregnant rhesus monkey
| Autor: | Su-Chen Li, Arthur J. Riopelle, Herman R. Seibold, Jack L. Smith, Robert H. Wolf, Charles W. Hill |
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| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Calorie Medicine (miscellaneous) Blood Pressure Biology Pregnancy Protein Deficiency Internal medicine Casein medicine Albuminuria Animals Young adult Nutrition and Dietetics Nutritional Requirements Albumin Blood Proteins medicine.disease Macaca mulatta Pregnancy Complications Endocrinology Blood pressure Liver Macaca Animal Nutritional Physiological Phenomena Female Dietary Proteins medicine.symptom Weight gain |
| Zdroj: | The American Journal of Clinical Nutrition. 28:20-28 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/28.1.20 |
| Popis: | Young adult female rhesus monkeys, maintained in a seminatural environment, when pregnant 30 days were fed a balanced semisynthetic diet containing 15.3% casein (13.4% protein) or 0.5, or 0.25 that amount for the remainder of their pregnancy. The diets,made isocaloricby the addition of carbohydrates to replace the missing casein, supplied 4, 2, or I g protein/kg per day if the animals ate 120 kcal/kg per day, an assumption thatwas reasonably accurate. We studied the responses of monkeys delivering normal young at term. All monkeys were clinically healthy during the experiment. All reduced theirtotalplasma protein concentration, principally by decreasing their albumin concentration. Greatest loss occurred in the low-protein group. Albuminuria was a common finding in all groups. Food consumption, though varying throughout pregnancy, remained fairly comparable from group to group. Weight gain of the highest protein group was greatest; that for the lowest protein group barely covered the weight of the products of conception. Blood pressure declined during pregnancy while blood glucose levels rose. There were no morphologic changes in hair bulbs and only suggestive changes in liver cells that pointed to increased vacuolation. Increased metabolic efficiency during pregnancy enables the mother to safely pass through a long pregnancy during most of which she is fed a low-protein diet. Nonpregnant animals suffer more under the same circumstances. Am. J. C'lin. Nut,'. 28: 20-28, 1975. |
| Databáze: | OpenAIRE |
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