Quantitative Analysis of Cu(I) Concentration in Click Chemistry — Biotinylation at Side Chain of Propargylglycine Using Click Chemistry under Heating Conditions

Autor: Yui Ogasawara, Yasuyuki Hashidoko, Makoto Hashimoto, Yuta Murai, Yasuko Sakihama
Rok vydání: 2012
Předmět:
Zdroj: HETEROCYCLES. 86:735
ISSN: 0385-5414
DOI: 10.3987/com-12-s(n)32
Popis: The click reaction is one of the latest techniques for the chemical modification of bioactive compounds. Chemical modifications of α-amino acid side chains are gaining significance as useful and important tools for biochemical research. Biotinylation at side chain of propargylglycine using click reaction was examined. The detail quantitative analysis of Cu(I) concentration are performed to proceed the click reaction effectively.
Databáze: OpenAIRE