Nivolumab exerts therapeutic effects against metastatic lesions from early gastric adenocarcinoma with a small proportion of neuroendocrine carcinoma after gastrectomy: a case report

Autor: Hiroshi Sawayama, Hideo Baba, Yoshihiro Komohara, Hiroki Hirao, Ichirou Yoshinaka, Kazunori Harada, Noboru Takata, Kazuya Sakata
Rok vydání: 2020
Předmět:
Zdroj: Clinical Journal of Gastroenterology. 13:759-765
ISSN: 1865-7265
1865-7257
DOI: 10.1007/s12328-020-01159-8
Popis: Gastric neuroendocrine carcinoma (NEC) is an aggressive disease with high metastatic ability. Gastric cancer has intra-tumoral and intra-patient heterogeneity and may contain NEC. We discuss the case of a 75-year-old man who underwent distal gastrectomy for early gastric cancer. Tumor pathology revealed that nearly all of the tumor (> 95%) was well-differentiated adenocarcinoma, with NEC detected in a small area (
Databáze: OpenAIRE