Nivolumab exerts therapeutic effects against metastatic lesions from early gastric adenocarcinoma with a small proportion of neuroendocrine carcinoma after gastrectomy: a case report
Autor: | Hiroshi Sawayama, Hideo Baba, Yoshihiro Komohara, Hiroki Hirao, Ichirou Yoshinaka, Kazunori Harada, Noboru Takata, Kazuya Sakata |
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Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty Adenocarcinoma Gastroenterology Ramucirumab Metastasis 03 medical and health sciences 0302 clinical medicine Gastrectomy Stomach Neoplasms Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Aged business.industry Gastric Neuroendocrine Carcinoma Cancer General Medicine medicine.disease digestive system diseases Carcinoma Neuroendocrine Early Gastric Cancer Irinotecan Nivolumab 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Neoplasm Recurrence Local business medicine.drug |
Zdroj: | Clinical Journal of Gastroenterology. 13:759-765 |
ISSN: | 1865-7265 1865-7257 |
DOI: | 10.1007/s12328-020-01159-8 |
Popis: | Gastric neuroendocrine carcinoma (NEC) is an aggressive disease with high metastatic ability. Gastric cancer has intra-tumoral and intra-patient heterogeneity and may contain NEC. We discuss the case of a 75-year-old man who underwent distal gastrectomy for early gastric cancer. Tumor pathology revealed that nearly all of the tumor (> 95%) was well-differentiated adenocarcinoma, with NEC detected in a small area ( |
Databáze: | OpenAIRE |
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