New perspectives for microbial glycolipid fractionation and purification processes
| Autor: | Gladys Nuissier, Imane Hadef, Romain Reynaud, Jean-Hugues Renault, Arnaud Guilleret, Jane Hubert, Karen Plé, Mahmoud Hamzaoui |
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| Přispěvatelé: | Institut de Chimie Moléculaire de Reims - UMR 7312 (ICMR), SFR Condorcet, Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Chimie des Substances Naturelles (ICMRCSN), Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-SFR Condorcet, Renault, Jean-Hugues |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
0106 biological sciences
Solvent system 0303 health sciences [CHIM.ANAL] Chemical Sciences/Analytical chemistry Chromatography Chemistry Centrifugal partition chromatography [CHIM.ORGA]Chemical Sciences/Organic chemistry General Chemical Engineering Extraction (chemistry) General Chemistry Fractionation [CHIM.ORGA] Chemical Sciences/Organic chemistry 01 natural sciences 6. Clean water 03 medical and health sciences Countercurrent chromatography Glycolipid High complexity [CHIM.ANAL]Chemical Sciences/Analytical chemistry 010608 biotechnology Purification methods ComputingMilieux_MISCELLANEOUS 030304 developmental biology |
| Zdroj: | Comptes Rendus. Chimie Comptes Rendus. Chimie, Académie des sciences (Paris), 2012, 15 (1), pp.18-28 |
| ISSN: | 1631-0748 1878-1543 |
| Popis: | Microbial glycolipids produced from renewable sources are of considerable interest in light of their promising biological activities and surfactant characteristics when compared to petroleum derived surfactants. Intense research efforts are currently being made to reduce their production costs and optimize recovery as selected mixtures through downstream processes. Due to the high complexity of natural glycolipid mixtures, efficient purification techniques are also required to examine the biological mechanisms of individual species towards human systems for their application in health-related areas. This review deals with recent advances in the development of glycolipid extraction, fractionation and purification methods, with a particular focus on solid support-free liquid-liquid separation techniques including centrifugal partition chromatography (CPC) and counter-current chromatography (CCC). These techniques offer promising perspectives for the preparative or large-scale separation of glycolipids from complex crude extracts, mainly because of their flexibility in solvent system selection and applicability to a diversity of structures of any polarity. |
| Databáze: | OpenAIRE |
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