Perioperative complications of esophagectomy: Postneoadjuvant treatment versus primary surgery - Our experience and review of literature
| Autor: | RC Mistry, KC Polavarapu, NV Gulavani, SS Sharma, Amit Patil, NP Dharmadhikari |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Carcinoma medicine Chi-square test Humans Prospective Studies Perioperative Period Neoadjuvant therapy Retrospective Studies business.industry Incidence (epidemiology) Significant difference Perioperative Middle Aged medicine.disease Neoadjuvant Therapy Surgery Esophagectomy Treatment Outcome Oncology 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female business Chemoradiotherapy |
| Zdroj: | Indian journal of cancer. 54(2) |
| ISSN: | 1998-4774 |
| Popis: | AIMS: To compare perioperative complications in esophagectomy after neoadjuvant therapy v/s primary surgery. SETTINGS AND DESIGN: Retrospective analysis of perioperative complications in a prospectively maintained data base of patients who underwent esophagectomy as Primary surgery or after neoadjuvant therapy was done. METHODS AND MATERIAL: 238 cases of esophagectomies performed for esophageal carcinoma were analysed and compared, out of which 125(52.5%) were given neoadjuvant therapy followed by surgery and 113(47.5%) underwent primary surgery. Surgical procedure was standard for both the groups. All the cases were analysed for perioperative complications. STATISTICAL ANALYSIS USED: Data was analysed using Open Epi soft ware. Association between the two study group was assessed with Chi square test. RESULTS: On comparison, both the groups were comparable in demographic profile and type of surgery performed. However, tumour stage was higher for cases who received neoadjuvant therapy as expected. On analysis there was no significant difference in overall morbidity and 30 days mortality. CONCLUSIONS: Neoadjuvant Chemo/chemoradiotherapy is a feasible option in esophageal carcinoma without increase in incidence of peri operative morbidity or mortality. |
| Databáze: | OpenAIRE |
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