Partial pressure of oxygen in adipose tissue and its relationship with fatness in a natural animal model of extreme fat deposition, the grey seal
| Autor: | Ryan Milne, Joel Rocha, Ailsa J. Hall, J. Chris McKnight, Kimberley A. Bennett, Simon Moss, Laura Oller |
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| Přispěvatelé: | NERC, University of St Andrews. School of Biology, University of St Andrews. Sea Mammal Research Unit, University of St Andrews. Scottish Oceans Institute, University of St Andrews. Marine Alliance for Science & Technology Scotland |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Physiology
Seals Earless Subcutaneous Fat Adipose tissue Hemoglobins Animal science Animal model Oxygen Consumption Physiology (medical) Blubber QP1-981 Animals SDG 14 - Life Below Water marine mammals Adiposity MCC QL adiposity Respiration Temperature temperature DAS Original Articles QL Zoology Po2 Oxygen blubber Oxygenation NIRS Research council Marine mammals Environmental science Original Article oxygenation Deposition (chemistry) |
| Zdroj: | Physiological Reports Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021) |
| ISSN: | 2051-817X |
| Popis: | Excessive adiposity is associated with altered oxygen tension and comorbidities in humans. In contrast, marine mammals have high adiposity with no apparent detrimental effects. However, partial pressure of oxygen (Po2) in their subcutaneous adipose tissue (blubber) and its relationship with fatness have not been reported. We measured Po2 and temperature at different blubber depths in 12 healthy juvenile grey seals. Fatness was estimated from blubber thickness and morphometric parameters. Simultaneously, we monitored breathing pattern; heart rate and arterial blood saturation with a pulse oximeter; and relative changes in total hemoglobin, deoxyhemoglobin, and oxyhemoglobin in blubber capillaries using near‐infrared spectroscopy (NIRS) as proxies for local oxygenation changes. Blubber Po2 ranged from 14.5 to 71.4 mmHg (39.2 ± 14.1 mmHg), which is similar to values reported in other species. Blubber Po2 was strongly and negatively associated with fatness (LME: p Grey seals blubber Po2 is similar to that measured in other mammal species and negatively associated with fatness, independently of depth of measurement, oxygen delivery, or temperature. |
| Databáze: | OpenAIRE |
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